BDBM50317345 (2-(3,4-dihydroxystyryl)-8-hydroxyquinolin-7-yl)(pyridin-4-yl)methanone::CHEMBL188701::{2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinolin-7-yl}-pyridin-4-yl-methanone

SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccncc4)c(O)c3n2)cc1O

InChI Key InChIKey=MWYLCGMRPWWKMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317345   

TargetSerine/threonine-protein kinase pim-1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50317345({2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
New York University

US Patent
LigandPNGBDBM50317345({2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-...)
Affinity DataIC50: 5.72E+4nMAssay Description:Commercially available 2-Hydroxyisoquinoline-1,3(2H,4H)-dione (CAS No: 6890-08-0), a well-known scaffold backbone used to develop human immunodeficie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent