BDBM50317482 (S)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)piperidin-1-yl)butanoic acid::CHEMBL1098790

SMILES OC(=O)CCCN1CCCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key InChIKey=LHVWRDUSOBRVEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317482   

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50317482((S)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)piper...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50317482((S)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)piper...)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed