BDBM50317581 4-(6-(2,4-difluorophenyl)-2-oxo-2H-quinolizin-1-yl)-3,5-difluorobenzamide::CHEMBL1098797

SMILES NC(=O)c1cc(F)c(c(F)c1)-c1c2cccc(-c3ccc(F)cc3F)n2ccc1=O

InChI Key InChIKey=QABNWWXOZYBHJD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317581   

TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317581(4-(6-(2,4-difluorophenyl)-2-oxo-2H-quinolizin-1-yl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse p38alpha after 3 hrs by SPA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317581(4-(6-(2,4-difluorophenyl)-2-oxo-2H-quinolizin-1-yl...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed