BDBM50317584 1-(2,6-difluoro-4-(1,3,4-oxadiazol-2-yl)phenyl)-6-(2,4-difluorophenyl)-2H-quinolizin-2-one::CHEMBL1098822

SMILES Fc1ccc(c(F)c1)-c1cccc2c(-c3c(F)cc(cc3F)-c3nnco3)c(=O)ccn12

InChI Key InChIKey=SUUWTKVQWYDNTC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317584   

TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317584(1-(2,6-difluoro-4-(1,3,4-oxadiazol-2-yl)phenyl)-6-...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of mouse p38alpha after 3 hrs by SPA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317584(1-(2,6-difluoro-4-(1,3,4-oxadiazol-2-yl)phenyl)-6-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed