BDBM50317589 (+)-S-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpiperazin-1-yl)ethyl)cyclohexanol::CHEMBL1095850

SMILES CN1CCN(C[C@H](c2csc(Cl)c2)C2(O)CCCCC2)CC1

InChI Key InChIKey=KHYNNQYNYMSTIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50317589   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317589((+)-S-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpipe...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human NET transfected in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317589((+)-S-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpipe...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human NET transfected in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317589((+)-S-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpipe...)
Affinity DataIC50: 212nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317589((+)-S-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpipe...)
Affinity DataIC50: 389nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed