BDBM50317649 6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl-1,4,7,10-tetraoxotetradecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-3-yl)-N-hydroxyhexanamide::CHEMBL1096985

SMILES ONC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

InChI Key InChIKey=OHPVTQHZRUJEEL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317649   

TargetHistone deacetylase 6(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317649(6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317649(6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human HDAC4 catalytic domain expressed in Escherichia coli BL21 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317649(6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of HDAC5 catalytic domain expressed in Escherichia coli after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed