BDBM50317858 CHEMBL1095556::cycloartobiloxanthone

SMILES CC1(C)C=Cc2c(cc(O)c3c(=O)c4c(oc23)-c2c(O)cc(O)c3c2[C@H](C4)C(C)(C)O3)O1

InChI Key InChIKey=OCZFLOUWXXGBPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317858   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
The Ohio State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317858BDBM50317858(cycloartobiloxanthone | CHEMBL1095556)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NFkappa p50 isolated from nuclear extract of human HeLa cells assessed as blockade of binding to biotinylated consesus sequence by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
The Ohio State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317858BDBM50317858(cycloartobiloxanthone | CHEMBL1095556)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells assessed as blockade of binding to biotinylated consesus sequence by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed