BDBM50318127 (15S)-17-amino-11,15-dicyclohexyl-2-oxa-11,16,18-triazatetracyclo[14.5.3.1^{3,7}.0^{19,23}]pentacosa-1(22),3(25),4,6,17,19(23),20-heptaen-12-one::CHEMBL1098734
SMILES NC1=Nc2ccc3Oc4cccc(CCCN(C5CCCCC5)C(=O)CC[C@@H](C5CCCCC5)N1Cc2c3)c4
InChI Key InChIKey=YRZGWNOJFXJXID-HKBQPEDESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50318127
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of BACE1 assessed as amyloid beta (1-40) productionMore data for this Ligand-Target Pair