BDBM50318188 6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL1098440

SMILES Clc1ccc(Cc2cc3c(Nc4cccc(c4)C#C)ncnc3[nH]2)c(Cl)c1

InChI Key InChIKey=FQFXJYXFHKOMBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318188   

TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human SF539 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of VEGFR1 phosphorylation in human A498 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of VEGFR2 phosphorylation in human U251 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of EGFR phosphorylation in human A431 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed