BDBM50318299 CHEMBL1097753::Methyl (4R)-5-Cyano-2,6-dimethyl-4-quinolin-4-yl-1,4-dihydropyridine-3-carboxylate

SMILES COC(=O)C1=C(C)N=C(C)C(C#N)[C@H]1c1ccnc2ccccc12

InChI Key InChIKey=QCWCXQNTRHJZKW-KPMSDPLLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318299   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318299(CHEMBL1097753 | Methyl (4R)-5-Cyano-2,6-dimethyl-4...)
Affinity DataIC50:  77nMAssay Description:Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed