BDBM50318313 3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-oxazolidin-3-yl}benzonitrile::CHEMBL1094763

SMILES CC(C)(C)c1ccc(OC[C@@H]2CN(C(=O)O2)c2cccc(c2)C#N)cc1

InChI Key InChIKey=YFJUDGZIRPWFBS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318313   

TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318313(3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-...)
Affinity DataEC50:  82nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318313(3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-...)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed