BDBM50318415 7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylmethoxy)-6-demethoxy-6,7,8,14-tetrahydro-6beta,14beta-endoetheno-oripavine::CHEMBL1094163

SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@]2(OCC4CC4)C=C[C@@]3(C[C@@H]2C(C)(C)C)[C@H]1C5

InChI Key InChIKey=KFUPOJIZZGXURM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318415   

TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318415BDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Debrecen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318415BDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318415BDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataIC50: 650nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed