BDBM50318636 3-(2-chlorophenyl)-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one::CHEMBL1082420

SMILES Oc1ccc2c(c1)oc(c(-c1ccccc1Cl)c2=O)C(F)(F)F

InChI Key InChIKey=NVWFOLBTOQENGO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318636   

TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50318636(3-(2-chlorophenyl)-7-hydroxy-2-(trifluoromethyl)-4...)
Affinity DataEC50:  33.8nMAssay Description:Agonist activity at ERbeta expressed in yeast assessed as alpha-galactosidase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50318636(3-(2-chlorophenyl)-7-hydroxy-2-(trifluoromethyl)-4...)
Affinity DataEC50:  59.1nMAssay Description:Agonist activity at ERalpha expressed in yeast assessed as alpha-galactosidase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50318636(3-(2-chlorophenyl)-7-hydroxy-2-(trifluoromethyl)-4...)
Affinity DataEC50:  753nMAssay Description:Agonist activity at ERbeta expressed in CHO-K1 cells by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50318636(3-(2-chlorophenyl)-7-hydroxy-2-(trifluoromethyl)-4...)
Affinity DataEC50:  970nMAssay Description:Agonist activity at ERalpha expressed in CHO-K1 cells by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed