BDBM50319245 2-(3-(1-phenyl-1H-pyrazol-3-yl)propanamido)benzoicacid::CHEMBL1086567

SMILES OC(=O)c1ccccc1NC(=O)CCc1ccn(n1)-c1ccccc1

InChI Key InChIKey=JTPKNNPOAKKBFI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319245   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319245(2-(3-(1-phenyl-1H-pyrazol-3-yl)propanamido)benzoic...)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]niacin from GRP109A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319245(2-(3-(1-phenyl-1H-pyrazol-3-yl)propanamido)benzoic...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319245(2-(3-(1-phenyl-1H-pyrazol-3-yl)propanamido)benzoic...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319245(2-(3-(1-phenyl-1H-pyrazol-3-yl)propanamido)benzoic...)
Affinity DataEC50:  9.50E+3nMAssay Description:Displacement of [3H]niacin from GRP109A receptor in presence of 4% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed