BDBM50319277 5-fluoro-4-methyl-2-(2-methyl-4-(3-(4-methylpiperazin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL1086460

SMILES CN1CCN(CCCOc2ccc(-c3nc4ccc(F)c(C)c4[nH]3)c(C)c2)CC1

InChI Key InChIKey=JVUHNEKBJYRDTQ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319277   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50319277(5-fluoro-4-methyl-2-(2-methyl-4-(3-(4-methylpipera...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50319277(5-fluoro-4-methyl-2-(2-methyl-4-(3-(4-methylpipera...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human histamine H4 receptor in SK-N-MC cells assessed as forskolin-stimulated cAMP release preincubated for 10 mins before forsko...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed