BDBM50319293 (+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(6-methyl-3,6-diazabicyclo[3.1.0]hexan-3-yl)propoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL1086038

SMILES Cc1cc(OCCCN2CC3C(C2)N3C)ccc1-c1nc2ccc(F)c(C)c2[nH]1

InChI Key InChIKey=SDOQBCOFSSDBJV-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319293   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50319293BDBM50319293((+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(6-methyl...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50319293BDBM50319293((+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(6-methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human histamine H4 receptor in SK-N-MC cells assessed as forskolin-stimulated cAMP release preincubated for 10 mins before forsko...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed