BDBM50319414 CHEMBL1085155::[3-(2-Methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3-trifluoromethyl-benzamide

SMILES Cn1nccc1-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1OCCN1CCCC1

InChI Key InChIKey=UAVPDLMEWXPRFE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319414   

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319414([3-(2-Methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319414([3-(2-Methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl...)
Affinity DataIC50: 23nMAssay Description:Inverse agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of inositol phosphate accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319414([3-(2-Methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl...)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed