BDBM50319688 1-(3-(1-benzyl-1,4-dihydroimidazo[4,5-c]pyrazol-5-yl)-4-methylphenyl)-3-(3-chloro-5-(trifluoromethyl)phenyl)urea::CHEMBL1085603

SMILES Cc1ccc(NC(=O)Nc2cc(Cl)cc(c2)C(F)(F)F)cc1-c1nc2c[nH]n(Cc3ccccc3)c2n1

InChI Key InChIKey=ZFQWBDUPVBBYTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319688   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50319688(1-(3-(1-benzyl-1,4-dihydroimidazo[4,5-c]pyrazol-5-...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human cRAF using [33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed