BDBM50319740 3,3-dimethyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]quinazolin-8-yl)butanamide::CHEMBL1086087

SMILES CC(C)(C)CC(=O)Nc1ccc-2c(CCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1

InChI Key InChIKey=AGMOCPFJNJCUEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319740   

LigandPNGBDBM50319740(3,3-dimethyl-N-(2-(4-sulfamoylphenylamino)-5,6-dih...)
Affinity DataIC50: 820nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319740(3,3-dimethyl-N-(2-(4-sulfamoylphenylamino)-5,6-dih...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed