BDBM50319821 1-(2-(2-(difluoromethoxy)-6-fluorophenyl)-1-phenylethyl)piperazine::CHEMBL1086275

SMILES FC(F)Oc1cccc(F)c1CC(N1CCNCC1)c1ccccc1

InChI Key InChIKey=FNRNKAMBXVROAU-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319821   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319821(1-(2-(2-(difluoromethoxy)-6-fluorophenyl)-1-phenyl...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319821(1-(2-(2-(difluoromethoxy)-6-fluorophenyl)-1-phenyl...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319821(1-(2-(2-(difluoromethoxy)-6-fluorophenyl)-1-phenyl...)
Affinity DataKi: >3.16E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319821(1-(2-(2-(difluoromethoxy)-6-fluorophenyl)-1-phenyl...)
Affinity DataIC50: 1.04E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed