BDBM50319830 (+)-1-(1-(4-fluorophenyl)-2-(2-(trifluoromethoxy)phenyl)ethyl)piperazine::(-)-1-(1-(4-fluorophenyl)-2-(2-(trifluoromethoxy)phenyl)ethyl)piperazine::1-(1-(4-FLUOROPHENYL)-2-(2-(TRIFLUOROMETHOXY)PHENYL)ETHYL)PIPERAZINE (ENANTIOMERIC MIX)::1-(1-(4-fluorophenyl)-2-(2-(trifluoromethoxy)phenyl)ethyl)piperazine::CHEMBL1084033

SMILES Fc1ccc(cc1)C(Cc1ccccc1OC(F)(F)F)N1CCNCC1

InChI Key InChIKey=SQSFWPVYWBTHEX-UHFFFAOYSA-N

Data  9 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50319830   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  5.09E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  5.09E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataKi:  5.09E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataIC50: 8.05E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataIC50: 8.05E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319830(CHEMBL1084033 | (+)-1-(1-(4-fluorophenyl)-2-(2-(tr...)
Affinity DataIC50: 9.64E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed