BDBM50319832 1-(2-(2-(cyclopropylmethoxy)phenyl)-1-phenylethyl)piperazine::CHEMBL1083706

SMILES C(Oc1ccccc1CC(N1CCNCC1)c1ccccc1)C1CC1

InChI Key InChIKey=AQGRUVIDIWOMIH-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319832   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319832(1-(2-(2-(cyclopropylmethoxy)phenyl)-1-phenylethyl)...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319832(1-(2-(2-(cyclopropylmethoxy)phenyl)-1-phenylethyl)...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319832(1-(2-(2-(cyclopropylmethoxy)phenyl)-1-phenylethyl)...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319832(1-(2-(2-(cyclopropylmethoxy)phenyl)-1-phenylethyl)...)
Affinity DataIC50: 2.96E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed