BDBM50320345 (S)-(2-methyl-4-(4-p-tolylphthalazin-1-yl)piperazin-1-yl)(phenyl)methanone::CHEMBL1083284

SMILES C[C@H]1CN(CCN1C(=O)c1ccccc1)c1nnc(-c2ccc(C)cc2)c2ccccc12

InChI Key InChIKey=NOHJOTARDCVDLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320345   

TargetSmoothened homolog(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50320345((S)-(2-methyl-4-(4-p-tolylphthalazin-1-yl)piperazi...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human SMO expressed in HEPM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed