BDBM50320355 CHEMBL1085503::phenyl(4-(4-p-tolylphthalazin-1-yl)piperazin-1-yl)methanone

SMILES Cc1ccc(cc1)-c1nnc(N2CCN(CC2)C(=O)c2ccccc2)c2ccccc12

InChI Key InChIKey=TXGXKZZXXYWZPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320355   

TargetSmoothened homolog(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50320355(phenyl(4-(4-p-tolylphthalazin-1-yl)piperazin-1-yl)...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human SMO expressed in HEPM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed