BDBM50320442 CHEMBL1085257::N-hydroxy-1-(2-methoxyethyl)-4-(4-(4-(phenylcarbamoyl)piperidin-1-yl)phenylsulfonyl)piperidine-4-carboxamide

SMILES COCCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(cc1)N1CCC(CC1)C(=O)Nc1ccccc1

InChI Key InChIKey=WVNVANHURONWTG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50320442   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  370nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed