BDBM50320882 CHEMBL1165682::Ethyl-4-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-2-carboxylate

SMILES CCOC(=O)C1=CC(C2C(=O)CC(C)(C)CC2=N1)c1ccc(F)cc1

InChI Key InChIKey=YSHAWDSMLPOQOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320882   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320882(Ethyl-4-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed