BDBM50321002 CHEMBL1164508::N-(4-(4-Fluorophenyl)thiazol-2-yl)-2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)propanamide

SMILES CS(=O)(=O)c1ccc(cc1)C(CC1CCOCC1)C(=O)Nc1nc(cs1)-c1ccc(F)cc1

InChI Key InChIKey=GEPMNRBHCPMKPW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321002   

TargetHexokinase-4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321002(N-(4-(4-Fluorophenyl)thiazol-2-yl)-2-(4-(methylsul...)
Affinity DataEC50:  1.18E+3nMAssay Description:Activation of human glucokinase expressed in Escherichia coli BL21(DE3) coexpressing G6PDH by spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed