BDBM50321256 1-tosyl-1H-pyrrol-2(5H)-one::CA inhibitor, 15::CHEMBL1163131
SMILES Cc1ccc(cc1)S(=O)(=O)N1CC=CC1=O
InChI Key InChIKey=RFSWKQLTYZGQPP-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50321256
Affinity DataKi: 406nM ΔG°: -8.71kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 534nM ΔG°: -8.55kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 2.31E+4nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.73E+4nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair