BDBM50321257 5-hydroxy-1-tosyl-1H-pyrrol-2(5H)-one::CA inhibitor, 16::CHEMBL1163554
SMILES Cc1ccc(cc1)S(=O)(=O)N1C(O)C=CC1=O
InChI Key InChIKey=LASNBXWNXQRYSO-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50321257
Affinity DataKi: 510nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 584nM ΔG°: -8.50kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 639nM ΔG°: -8.44kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 1.46E+4nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair