BDBM50321552 CHEMBL1170582::N1-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-N4-methylterephthalamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(cc3)C(=O)NC)sc12

InChI Key InChIKey=QMZCIVSHZATIOB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321552   

TargetAdenosine receptor A2b(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321552(N1-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321552(N1-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321552(N1-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed