BDBM50321574 (S)-5-acetyl-N-(2,3-dihydroxypropoxy)-4-fluoro-2-(2-fluoro-4-iodophenylamino)-1-methyl-1H-pyrrole-3-carboxamide::CHEMBL1171015

SMILES CC(=O)c1c(F)c(C(=O)NOC[C@@H](O)CO)c(Nc2ccc(I)cc2F)n1C

InChI Key InChIKey=OFRNQBJOWHENNK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321574   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50321574((S)-5-acetyl-N-(2,3-dihydroxypropoxy)-4-fluoro-2-(...)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
12/31/2012
Entry Details Article
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