BDBM50321649 3,6-di(1H-pyrazol-4-yl)imidazo[1,2-a]pyrimidine::CHEMBL1171532

SMILES c1n[nH]cc1-c1cnc2ncc(cn12)-c1cn[nH]c1

InChI Key InChIKey=IWEUEANCBZFPCW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321649   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50321649(3,6-di(1H-pyrazol-4-yl)imidazo[1,2-a]pyrimidine | ...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CHK1 by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50321649(3,6-di(1H-pyrazol-4-yl)imidazo[1,2-a]pyrimidine | ...)
Affinity DataIC50:  440nMAssay Description:Inhibition of ABL1 by Z-lite assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50321649(3,6-di(1H-pyrazol-4-yl)imidazo[1,2-a]pyrimidine | ...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed