BDBM50321726 CHEMBL1172449::cyanopeptolin 1020

SMILES CCCCCC(=O)NC(CCC(=O)[O-])C(=O)NC1C(=O)NC(CCC[NH+]=C(N)N)C(=O)NC2CCC(O)N(C2=O)C(Cc2ccccc2)C(=O)N(C)C(Cc2ccc(O)cc2)C(=O)NC(C(C)C)C(=O)OC1C

InChI Key InChIKey=KFVBBPKAYRQLIL-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321726   

TargetCoagulation factor XI(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321726BDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321726BDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 490nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321726BDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321726BDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321726BDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 6.05E+5nMAssay Description:Inhibition of human LMW urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed