BDBM50321811 (4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid 1-{[(2R,3S)-2-tert-butylthio-5-oxo-tetrahydrofuran-3-ylcarbamoyl]-methyl}-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester::CHEMBL1171866

SMILES CC(C)(C)S[C@H]1OC(=O)C[C@@H]1NC(=O)CN1c2ccccc2C(=N[C@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)C1=O)c1ccccc1

InChI Key InChIKey=NNERGVKRVXDURE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321811   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50321811((4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid ...)
Affinity DataKi:  700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain after 10 to 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50321811((4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid ...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 after 10 to 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed