BDBM50321863 5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide::5-chloro-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)indoline-1-carboxamide::CHEMBL59097

SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(Cl)ccc23)cn1

InChI Key InChIKey=KXFAFOLRVYUQGO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321863   

Target5-hydroxytryptamine receptor 2C(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50321863(5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]mesulergine from human cloned 5HT2C receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50321863(5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50321863(5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50321863(5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]methylspiperone from human cloned 5HT2A receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50321863(5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed