BDBM50321872 4-Iodo-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide::4-iodo-5-methyl-N-(pyridin-3-yl)indoline-1-carboxamide::CHEMBL42276

SMILES Cc1ccc2N(CCc2c1I)C(=O)Nc1cccnc1

InChI Key InChIKey=IFMKJNSSPPAQOQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321872   

Target5-hydroxytryptamine receptor 2C(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50321872(4-iodo-5-methyl-N-(pyridin-3-yl)indoline-1-carboxa...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]mesulergine from human cloned 5HT2C receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50321872(4-iodo-5-methyl-N-(pyridin-3-yl)indoline-1-carboxa...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50321872(4-iodo-5-methyl-N-(pyridin-3-yl)indoline-1-carboxa...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK 293 cells using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50321872(4-iodo-5-methyl-N-(pyridin-3-yl)indoline-1-carboxa...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]methylspiperone from human cloned 5HT2A receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed