BDBM50322322 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(2-nitrophenyl)acrylate::CHEMBL1173789

SMILES Cc1ncc(n1CCOC(=O)\C=C\c1ccccc1[N+]([O-])=O)[N+]([O-])=O

InChI Key InChIKey=LMJANEYNZOFINJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322322   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322322((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322322((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed