BDBM50322323 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(2-methoxyphenyl)acrylate::CHEMBL1171273

SMILES COc1ccccc1\C=C\C(=O)OCCn1c(C)ncc1[N+]([O-])=O

InChI Key InChIKey=CTAHCBONHHOZRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322323   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322323((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322323((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed