BDBM50322335 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-isopropylphenyl)acrylate::CHEMBL1173714

SMILES CC(C)c1ccc(\C=C\C(=O)OCCn2c(C)ncc2[N+]([O-])=O)cc1

InChI Key InChIKey=XTUYBOXHWRYPPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322335   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322335((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4...)
Affinity DataIC50: 6.82E+3nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322335((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4...)
Affinity DataIC50: 9.97E+3nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed