BDBM50322966 7-(6-chloro-1H-benzo[d]imidazol-2-yl)-2-(3-chloro-4-fluorophenyl)-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonan-1-one::CHEMBL1210900

SMILES Fc1ccc(cc1Cl)N1C(c2ccccn2)C2(CCN(CC2)c2nc3ccc(Cl)cc3[nH]2)C1=O

InChI Key InChIKey=GMHHJIDHWAEXMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322966   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322966(7-(6-chloro-1H-benzo[d]imidazol-2-yl)-2-(3-chloro-...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322966(7-(6-chloro-1H-benzo[d]imidazol-2-yl)-2-(3-chloro-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed