BDBM50323091 2-(4-methoxy-3-(trifluoromethyl)phenyl)-9H-purine-6-carbonitrile::CHEMBL1209530

SMILES COc1ccc(-c2nc(C#N)c3[nH]cnc3n2)cc1C(F)(F)F

InChI Key InChIKey=YTVQPMYKXWVGGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323091   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323091BDBM50323091(2-(4-methoxy-3-(trifluoromethyl)phenyl)-9H-purine-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323091BDBM50323091(2-(4-methoxy-3-(trifluoromethyl)phenyl)-9H-purine-...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed