BDBM50323243 1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(trifluoromethyl)phenyl)-1H-pyrrolo[3,2-c]pyridine-4-carbonitrile::CHEMBL1209200

SMILES Cn1ccc2c(nc(cc12)-c1ccc(OCCN2CCCC2=O)c(c1)C(F)(F)F)C#N

InChI Key InChIKey=LXVXQOHLOGZNAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323243   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323243(1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(...)
Affinity DataIC50: 661nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323243(1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed