BDBM50323268 6-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209859

SMILES N#Cc1nc(-c2ccc(OCCCO)c(C(F)(F)F)c2)cc2nc[nH]c12

InChI Key InChIKey=QQAYZRPIXPBGKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323268   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323268BDBM50323268(6-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323268BDBM50323268(6-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed