BDBM50323269 6-(4-propoxy-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209858

SMILES CCCOc1ccc(-c2cc3nc[nH]c3c(C#N)n2)cc1C(F)(F)F

InChI Key InChIKey=AAIAIAXTLDUXPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323269   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323269BDBM50323269(6-(4-propoxy-3-(trifluoromethyl)phenyl)-1H-imidazo...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323269BDBM50323269(6-(4-propoxy-3-(trifluoromethyl)phenyl)-1H-imidazo...)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed