BDBM50323270 6-(4-(2-hydroxyethoxy)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209857

SMILES N#Cc1nc(-c2ccc(OCCO)c(C(F)(F)F)c2)cc2nc[nH]c12

InChI Key InChIKey=XFRQPGFEYYYCRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323270   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323270BDBM50323270(6-(4-(2-hydroxyethoxy)-3-(trifluoromethyl)phenyl)-...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323270BDBM50323270(6-(4-(2-hydroxyethoxy)-3-(trifluoromethyl)phenyl)-...)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed