BDBM50323272 6-(4-methoxy-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209855

SMILES COc1ccc(-c2cc3nc[nH]c3c(C#N)n2)cc1C(F)(F)F

InChI Key InChIKey=MDCJAGCSGKNBKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323272   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323272BDBM50323272(6-(4-methoxy-3-(trifluoromethyl)phenyl)-1H-imidazo...)
Affinity DataIC50: 339nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323272BDBM50323272(6-(4-methoxy-3-(trifluoromethyl)phenyl)-1H-imidazo...)
Affinity DataIC50: 8.51E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed