BDBM50323482 CHEMBL1209286::N-((2S,3R)-4-(1-(3-(1,3-dioxepan-5-yl)phenyl)cyclohexylamino)-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl)acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1cccc(c1)C1CCOCOC1

InChI Key InChIKey=SNCUIVJNMNJXKM-WHWDJVTISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323482   

TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50323482(CHEMBL1209286 | N-((2S,3R)-4-(1-(3-(1,3-dioxepan-5...)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant BACE-1 expressed in Escherichia coli after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed