BDBM50323773 CHEMBL1214007::N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-bromophenyl)nortropane

SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(Br)cc1)N2C\C=C\CF

InChI Key InChIKey=FXIKVFNIIRHKBX-PMWAWBRWSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323773   

TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50323773(CHEMBL1214007 | N-((E)-4-Fluorobut-2-en-1-yl)-2bet...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]RTI55 from human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50323773(CHEMBL1214007 | N-((E)-4-Fluorobut-2-en-1-yl)-2bet...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H](R,S)-citalopram HBr from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50323773(CHEMBL1214007 | N-((E)-4-Fluorobut-2-en-1-yl)-2bet...)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed