BDBM50324274 (Z)-N-Methyl-3-(4-oxo-2-{[2-oxo-5-(phenylsulfonamido)-indolin-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)-propanamide::CHEMBL1215282

SMILES CNC(=O)CCc1c(C=C2C(=O)Nc3ccc(NS(=O)(=O)c4ccccc4)cc23)[nH]c2CCCC(=O)c12

InChI Key InChIKey=CEUGFEWLHGCQEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324274   

TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324274((Z)-N-Methyl-3-(4-oxo-2-{[2-oxo-5-(phenylsulfonami...)
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324274((Z)-N-Methyl-3-(4-oxo-2-{[2-oxo-5-(phenylsulfonami...)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed