BDBM50324328 2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bipyridinyl-4-carboxylic Acid Amide::CHEMBL1215075

SMILES NC(=O)c1cc(nc(c1)-c1ccnc(Nc2ccccc2Cl)c1)N1CCNCC1

InChI Key InChIKey=VDRJYOAEHZMFEB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324328   

TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Affinity DataEC50:  478nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed